ESCMID Conference on Reviving and redeveloping old antibiotics

22 – 24 October 2014, Vienna, Austria

This conference presents and summarises currently available knowledge regarding optimised clinical use of old revived antibiotics and will discuss gaps of knowledge and future areas of research as well as adapting breakpoints, enriching treatment guidelines, and implications for regulatory issues. The major expectation for this conference is to drive the optimised usage of old antibiotics, especially indications and dosage regimens, as a key contribution to preserving the efficacy of these essential drugs in an era of escalating multi-drug resistance.

Target Audience

Specialists or physicians in training in infectious diseases, clinical microbiology and other disciplines dealing with antibacterial therapy, guideline developers, clinical pharmacists, pharmacologists, drug development scientists, regulatory specialists, health-care policy influencers.

Scientific Programme Topics

  • Available old antibiotics in Europe
  • Clinical and non-clinical “re-development” process of old antibiotics
  • Dose finding in the antibacterial drug development process
  • Progress in our understanding of optimised dosing
  • Clinical experience with dose optimisation programmes
  • Individualised dosing strategies
  • PK/PD models and their clinical relevance
  • PK/PD in special patient groups (e.g. children, elderly, obese, ICU patients)
  • Optimising usage of beta-lactams, fluoroquinolones, aminoglycosides, linezolid, vancomycin, daptomycin, colistin
  • Breakpoints
  • Prevention of emergence of resistance
  • Duration of therapy
  • Combination therapy
  • Exposure-toxicity relationships
  • Therapeutic drug monitoring concepts
  • Clinical decision tools to support individualised dosing of antibacterial drugs
  • Regulatory update

Scientific Committee

Rafael Cantón, Madrid, ES
Christian Giske, Stockholm, SE
Gunnar Kahlmeter, Växjö, SE
Leonard Leibovici, Tel Aviv, IL
Alasdair MacGowan, Bristol, UK
Johan Mouton, Nijmegen, NL
Roger Nation, Melbourne, AU
Mical Paul, Tel Aviv, IL
Ursula Theuretzbacher, Vienna, AT
John Turnidge, Adelaide, AU
Françoise Van Bambeke, Brussels, BE

Scientific Secretariat: Ursula Theuretzbacher

ESCMID Executive OfficeNora Nedkov
P.O. Box 214
4010 Basel, Switzerland
Phone +41 61 508 01 52
Fax +41 61 508 01 51

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